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Managing side effects during dose increases Gastrointestinal side effects such as nausea, vomiting, and diarrhea are common while taking GLP-1 medication and usually appear during the start of the medication or when the dose is increased

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Seek refrigeration wherever possible (hotel reception desks, pharmacy cold storage, restaurant kitchens, or convenience stores will sometimes hold medication briefly)

Do consider escalation when appetite has returned, adherence is solid, nutrition is adequate, side effects are tolerable, and metabolic goals are not being met