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10.1007/s00125-014-3217-9[Epub ahead of print]
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A steady reduction in astrocytic glutamate transporters, reduced capacity to buffer and disperse K + , and an overall decrease in their ability to sense synaptic activity (partly due to reduced density of ionotropic receptors) was also observed in aged mice (2024-months-old), disrupting long-term potentiation of synapses in the hippocampus (Lalo et al., 2011
doi: 10.4103/1673-5374.232488 63 UosefAVaughnNChuXElshawwafMAbdelshafyAElsaidKet al
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