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References 1.Meena R., Prajapati S.K., Nagar R., Porwal O., Nagar T., Tilak V.K., Jayakumararaj R., Arya R.K.K., Dhakar R.C

This combination treatment alleviated multiple disorders in in vivo experiments, including cardiomyocyte hypertrophy, glucose and insulin tolerance, and Alzheimers disease, and is currently being tested in multiple clinical studies for different age-related diseases

To calculate the EE%, the following equation was used: In vitro drug release A modified method using dialysis bag was utilized to assess the behavior of LUT release after being loaded in exosomes

These compounds have been also tested in two now completed phase-II and -III trials for the treatment of systemic lupus erythematosus [310] and diabetes mellitus type 1 [311] respectively, showing progressive improvement in disease activity thereby opening the way for new treatment perspectives