The typical switching profile: Started Zepbound through insurance with a reasonable copay ($50 to $150) Insurance coverage changed (job change, plan renewal, formulary update) New copay jumped to $300 to $600 per month Patient called Costco to check cash price, found it over $1,000 Patient researched compounded alternatives and switched to FormBlends The second common pattern: Medicare patient, retired, fixed income Part D plan covers Zepbound with $400 to $500 specialty copay Cannot use Lilly savings card (Medicare exclusion) Annual Zepbound cost would be $4,800 to $6,000 Switches to compounded tirzepatide at $2,148 to $3,348 annually The third pattern: Self-employed or between jobs, no insurance Paying Costco cash price ($1,000+ per month) Cannot sustain $12,000+ annual cost Switches to compounded at $179 to $279 per month What we don't see: patients with stable commercial insurance and $25 copays switching to compounded
Focus on compound movements with progressive overload
Watt and Marcus (1971 Watt, J., and A
Polyols (sugar alcohols): Many low-calorie foods, protein bars, and diet products contain polyols such as sorbitol, xylitol, or maltitol
