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For example, MIA downregulates the genes involved in axonal guidance, neurogenesis, and the cytoskeleton, whereas it upregulates the genes involved in translation, cell cycle, and DNA damage [50]

Andrea Zaenglein, professor of dermatology at Penn State, has noted: "For women with persistent hormonal acne driven by receptor sensitivity rather than elevated androgens, spironolactone may function as a long-term maintenance medication, much like we use isotretinoin-era patients on low-dose retinoids indefinitely" 10

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treatment with AntA of cells grown on galactose and treatment with paraquat