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The molecule cycles between its reduced (GSH) and oxidized (GSSG) forms, donating electrons to neutralize reactive oxygen species (ROS) either directly or through glutathione peroxidase-catalyzed reactions

The mechanisms sustaining this heterogeneity are unknown, although it should be acknowledged that CVOTs lack the statistical power to reliably detect differences in specific MACE components

The mechanism of ferroptosis is still under investigation, and some of the mechanistic studies described in this review need to be translated into clinical practice as soon as possible

Before laboratory use, reconstitute using sterile bacteriostatic water while following all appropriate sterile laboratory handling procedures and institutional safety protocols