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Possible side effects include nausea, vomiting, or diarrhea

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Based on how the peptides work, CJC-1295 generally takes longer to produce noticeable effects because it raises growth hormone activity gradually over time

(91) found that the destruction of vagal afferent fibers by capsaicin or lesions to subdiaphragmatic vagal fibers abolished ghrelin-induced feeding and substantially decreased c-fos expression in the ARC, where vagal afferents terminate, in response to ghrelin in capsaicin-treated rats