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In AWARD-11, waist circumference dropped 2.53 cm on higher doses
In[11] the half life for gastric emptying was calculated to be 7 minutes for oral liquid doses and overnight fasting
These results were well predicted by the plasma stability of the hybrids as all the compounds ( 2 , 5 and 9 ) with similar plasma stability to peptide 1 gave comparable results in vivo
No clinically relevant difference in the pharmacokinetics of TRESIBA was identified in a study comparing healthy subjects and subjects with kidney impairment including subjects with end stage kidney disease [see CLINICAL PHARMACOLOGY ]
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