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In a separate study , published in JAMA in August 2025, the same researchers found that, across ages, GLP-1s were associated with lower risk of some obesity-related cancers, such as endometrial, ovarian, and meningioma cancers, but with an increased risk of kidney cancer, and nonsignificant changes for several other cancers

The innovation pipeline is now dominated by a critical debate surrounding dual agonists versus single agonists, with multi-receptor compounds demonstrating superior clinical outcomes

These side effects are not uncommon with medications like semaglutide, as they can impact the daily lives of individuals who rely on this treatment