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GLP-1 receptor agonists have been shown to increase dopamine and serotonin release in the brain, which may contribute to their effects on appetite and satiety

Steinberg JP, Takamiya K, Shen Y, Xia J, Rubio ME, Yu S et al (2006)

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Pinch a fold of skin and insert the needle at a 45 to 90 degree angle depending on your body composition