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10.1016/j.ymthe.2022.05.020 72 YuK.WangC.LiY.JiangZ.YangG.WangY

The trial includes a 48-week primary treatment period, blinded to bimagrumab study drug, followed by a 24-week open-label treatment extension period, and a subsequent 32-week follow-up period after treatment withdrawal

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Any other effect can be considered as a pleiotropic, off-target effect, or in the case of unwanted actions, adverse effects ( Figure 1 )