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These mediators not only drive neuroinflammation but also directly damage myelin and oligodendrocytes

To overcome this limitation, research efforts have been devoted to the development of therapeutic agents with biological mechanisms of action that are independent of the oxygen concentration

Since these foci did not co-localise with ICP4, a classical marker of viral replication compartments 81 , and only formed in the presence of C-nuclear capsids, we initially considered they might be mature DNA-containing capsids ready to exit the nucleus

A study showed that serum sTFR levels were significantly higher and serum iron levels were significantly lower in patients with RA compared to healthy controls