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Future research must prioritize large-scale, multicenter trials using validated surrogate markers (e.g., FibroScan, HVPG) followed by long-term observation of hard clinical outcomes to provide high-confidence evidence for clinical practice (Zhang et al., 2013)

GLP-1 receptor agonists work by mimicking GLP-1, a naturally occurring hormone involved in blood sugar regulation and appetite signaling

Based on the latest research

Katie summarizes the four key studies supporting the citrulline-glutathione combination, including the newer research by Abby Smith Ryan examining flow-mediated dilation rather than plasma nitrates