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Consistent use over several weeks or even months is often needed to see significant changes

International journal of physiology, pathophysiology and pharmacology , 4 (2), 5973

Free Radical Biol Med 46:11771185

En diseos in vitro, las curvas dosis-respuesta suelen abarcar rangos nanomolares para caracterizar la activacin de IGF-1R y la sealizacin PI3K/Akt, ajustando concentraciones segn el tipo celular