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Additionally, a study showed that knockdown of CLEC16A, which encodes an E3 ubiquitin ligase that controls mitophagic flux in cells, impaired mitophagy, leading to the aggravation of apoptosis in cells treated with proinflammatory cytokines [110]

In conclusion, current exclusive e-cigarette use was associated with lower odds of prevalent hypertension compared with never users in conventionally adjusted models, an association concentrated among former smokers who had switched to vaping

Roemer E, Tewes FJ, Meisgen TJ, Veltel DJ, Carmines EL (2002) Evaluation of the potential effects of ingredients added to cigarettes

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