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: 174,2 | : NNMT (-N-) | : NAD+/SAM/ | : + , NNMT , 5-Amino-1MQ , NNMT

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The discovery that NNMT expression is dramatically elevated in adipose tissue of obese humans and animal models, and that NNMT inhibition or knockdown prevents diet-induced obesity and improves metabolic health, has catalyzed intense research interest in NNMT as a therapeutic target for obesity, metabolic syndrome, and related conditions

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