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Corella-Salazar DA, Domnguez-Avila JA, Montiel-Herrera M, et al

Phase 2 Results That Led to Phase 3 Retatrutide's Phase 2 trial results, published in the New England Journal of Medicine in June 2023, were strong enough that Eli Lilly fast-tracked it into one of the largest Phase 3 obesity programs ever run

Mechanism of Action Comparison# Cortistatin# Cortistatin promotes slow-wave sleep through a well-characterized mechanism centered on cortical synchronization