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Article PubMed CAS Google Scholar Dahlin LB, Zimmerman M, Calcagni M, Hundepool CA, Van Alfen N, Chung KC (2024) Carpal tunnel syndrome

Any of these make an auto-immune cause of B12 deficiency (PA, also called autoimmune gastritis 3 ) more likely

Mechanism of action Cagrilintide is modified amylin: natural 37 amino acid sequence + conjugated C20-fatty acid via linker (like semaglutide) plasma albumin binding half-life extension from 12 min to ~7 days weekly dosing

Fasting insulin and HOMA-IR (a measure of insulin resistance) decreased substantially at all active doses, with the greatest reductions at 8mg and 12mg