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A study of the 2009 federal tax increase on smokeless tobacco led to at least 135,000 fewer users immediately after the increase took effect

In addition, the modest sample size may have been responsible for the whole group interaction between the PET/CT and 5C-CPT findings not being significant and the WB SUV findings not being significantly different between HIV- smokers and non-smokers as was found in prior research [37, 38], though it should be noted that a mean group difference (8.0%) between the HIV- smoker and non-smoker groups was found in the expected direction

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By the third season, ratings were suffering, and Roddenberry was exhausted by refereeing between Shatner (Kirk) and Leonard Nimoy (Spock)