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Alcohol would not fall under the category of an essential nutrient because not having it in your diet does not lead to any sort of deficiency

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The Ontario Drug Benefit (ODB) database was used to identify patients who were prescribed vitamin B12 injections, and the Ontario Health Insurance Plan database was used to identify all physician claims for intramuscular injections as well as laboratory tests assessing vitamin B12 levels

Taken together, these findings therefore confirmed that any differences that we identified in inflammatory gene expression in AT were related to any changes in circulating lipids thereby suggesting an early inflammatory AT phenotype may be a mechanism that underlies the development of metabolic disorders as a consequence of low B12 levels in maternal obesity