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It is based on the different product

Oak Street Health cofounder Geoff Prices decision to join Knownwells board underscores that lineage: both organizations prove that better outcomes and lower costs can coexist

Tirzepatide has had even more substantial outcomes with over 50% losing more than 20% of their body weight, a BMI reduction of up to 10 points and similar improvements in blood pressure, A1C, CRP and cholesterol levels

It separately flags reduced benefit and higher risk for people over 65, those on medications affecting kidney function such as ACE inhibitors and NSAIDs, and those with severe gastrointestinal dysfunction