fda compounding semaglutide crackdown november 2025 Warns on Certain Forms of Compounded How FDA Crackdowns Are Affecting

& Devaraj, S

Gastrointestinal Fluid Loss The most common GLP-1 side effects are gastrointestinal: Nausea: 44% of Wegovy users, 56% of Zepbound users Vomiting: Increases relative risk 2.90-2.95x vs placebo Diarrhea: Common across all GLP-1 medications Each episode of vomiting or diarrhea depletes 100-500mg of sodium plus potassium, magnesium, and calcium

The formulation follows physician supervised guidelines and is prepared and administered by licensed professionals

And it doesn't come with the food and water restrictions that come with Novo's oral option, which requires people wait 30 minutes after taking the drug to eat and drink