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Chronic neuroinflammation has been reported to contribute to serotonergic, dopaminergic, and noradrenergic dysfunction in the brain (Song and Wang, 2011) and to lead to chronic immune dysregulation (Carvalho et al., 2013)

A history of severe reflux, bariatric surgery, opioid use, Parkinson disease, scleroderma, gastric outlet obstruction, or long-standing diabetes should raise suspicion for baseline motility impairment

Supplementary Figure S3 shows the distribution of the years at the initiation of treatment depending on the drug

Inaccurate Documentation : Failing to document symptoms and test results can lead to denials