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Their use, however, is associated with some serious side effects, including kidney and liver failure, and gastrointestinal bleeding ( 2 O 2 -induced damage more effectively than DFO (Persson and Richardson, 2005)

Several recent CVOTs have shown that GLP-1RAs can reduce the decline of estimated GFR (eGFR) and delay the onset of the occurrence of proteinuria in patients with T2DM [4, 22, 26, 46, 47]

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doi: 10.1016/S2213-8587(13)70214-6 231 DunganKMPovedanoSTForstTGonzlezJGAtissoCSeallsWet al