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Using a model of streptozotocin diabetes in rats in vivo and HT-22 cells in vitro, it was shown that GLP-1RA liraglutide improves the cognitive abilities of rats with diabetes mellitus and can have a protective effect by reducing oxidative stress, suppressing the expression of -secretase (BACE1) and -secretase, as well as reducing the deposition of -amyloid by triggering signaling mechanisms associated with NF-kB and ERK1/2 [30]

Dhingra, S., Qureshi, R., Abdellatif, A., Gaber, L

Proper disposal of used needles in FDA-cleared sharps containers is essential for safety

Routes of Administration Subcutaneous injection (standard): At the 1 mg community-standard dose, injection volume is small (0.2 mL)