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Rushing any single step is the usual cause of a failed batch

CHAC1 is primarily regulated by the UPR pathway, specifically the PERK/eIF2/ATF4/ATF3/CHOP cascade, which is activated under conditions of ER stress

Micronutrients To increase cellular energy production efficiently, optimal levels of critical nutrients and enzyme cofactors must be achieved

Peer review Peer review information Nature Communications thanks Nicolas Rouhier and Mirko Zaffagnini for their contribution to the peer review of this work