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He told 60 Minutes that he had gone to ask Sandefur about it and that Sandefur had been harsh: I dont want to hear any more discussion about a safe cigarette. We pursue a safer cigarette, it would put us at extreme exposure with every other project. (On 60 Minutes, B&W said this was false.) Wigand made no secret of his lack of respect for Sandefur: I wouldnt consider them all intellectual titans

Also, nicotine significantly induces vascular smooth muscle cells proliferation via the upregulation of bFGF mitogen and several MMPs, which leads to an augmentation of lesions and development of intimal hyperplasia, atherosclerosis, and aneurysm

The inclusion of menthol in policies is long overdue, and a current lawsuit from the The African American Tobacco Control Leadership Council (AATCLC) and Action on Smoking and Health (ASH) calls for action from the FDA

Aragon G, Younossi ZM (2010) When and how to evaluate mildly elevated liver enzymes in apparently healthy patients