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Serum levels drop roughly 60% between age 20 and age 60, which is the core rationale for exogenous replacement
Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V
A Cleveland Clinic review notes that one case report described symptoms only after a cumulative 15,000 mcg (15 mg) of injected B12 over several weeks
Regulatory agencies have warned about potential toxicity to the liver, kidneys, and nervous system
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