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Sources of the following include the OPC, Salem Health and the Mayo Clinic: One bit of research is certain, however: THC levels in today's pot are higher, so its effect is stronger

Nicotine suppresses Parkinsons disease like phenotypes induced by Synphilin-1 overexpression in Drosophila melanogaster by increasing tyrosine hydroxylase and dopamine levels

In addition, unlike the middle-aged and elderly who are sensitive to nicotine and tar content, the nicotine and tar content tended to be high, unlike the light design, perhaps because it was sought by the younger generation