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The leptin receptor is found on many cells (including the hypothalamus) and mediates leptin actions in fat-energy balance, sleep, thirst, and body temperature - especially in relation to the bodys Circadian rhythms

RSL3 inhibits mTOR signaling in thyroid cancer cells The mTOR signaling pathway has recently been implicated in counteracting ferroptosis by regulating ROS production 20 , therefore, it was important to examine the effects of RSL3 on mTOR signaling pathway and its downstream proteins and whether inactivation of mTOR pathway signaling will occur in thyroid cancer cells with GPX4 inhibition

References Konstantinopoulos, P

Summary Keywords topiramate, migraine, oxidative stress, neurogenic inflammation, ferroptosis Citation Chen Q-W, Meng R-T and Ko C-Y (2024) Modulating oxidative stress and neurogenic inflammation: the role of topiramate in migraine treatment