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Treatment with dopamine (5 10 5 M) increased the proliferation of the immature murine osteoblast cell line MC3T3-E1 (Lee, Tsang et al., 2015), although in another study using this cell line, dopamine suppressed osteoblast mineralization and osteoblast marker expression that was not seen in primary murine osteoblasts (Motyl et al., 2017)