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Melanotan 2 has no marketing authorization from the FDA, the EMA, or any comparable regulator, and (as noted above) the FDA approval of the Melanotan-2-derived molecule bremelanotide/Vyleesi does not launder Melanotan 2 into an approved product

93 Additionally, tirzepatide, a dual GIP/GLP-1 receptor agonist, has gained prominence following USFDA approval in 2023 for weight management in adults with obesity or overweight and has demonstrated robust efficacy in RCTs

The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial

These are illustrative concerns, not a contraindication checklist there is no approved indication