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This is supported by studies using neurons differentiated from patient-derived induced pluripotent stem cells (iPSC), which were found to display hyperexcitability and increased intracellular Ca 2+ levels, as well as increased transcription of genes involved in Ca 2+ -signalling, compared with neurons derived from healthy unaffected controls [19, 20]
Benjamin Duffy, an Obesity Medicine Specialist at ThedaCare, emphasizes that a provider-guided tapering process typically takes about two months
1 Clinical Use of GLP-1 and GLP-1/GIP RAs Approved Agents and Dosing GLP-1 RAs have a relatively long half-life of approximately one week
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