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How Weight Loss Drugs Went Mainstream These medications (particularly Ozempic, Wegovy, and Mounjaro) quickly gained attention after celebrities began using them for cosmetic weight loss

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In clinical studies, GLP-1 receptor agonists have been associated with modest reductions in LDL cholesterol and total cholesterol, with more variable effects on triglycerides depending on the specific agent and study population

There were no significant differences in the protein and mRNA expression levels of GPX4, GCLM, p62, Nrf2, HO-1, Keap1 and FTH