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A number of studies have also found a dose response effect in the increased risk

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In her assessment of the Ankeny, Iowa-based chains quarterly results, Bonnie Herzog, managing director of beverage, tobacco and convenience-store research for Wells Fargo Securities, New York, said Caseys experienced weak consumer demand in farm-belt markets, overall softness in restaurants and food retail, a deceleration of cigarette sales and a reversal of recent uptrading trends and a general food deflation. For us, if you look at fiscal 2017, the best-case scenario is margins will be stable to slightly down in the cigarette category, said Bill Walljasper, CFO of Caseys