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Because some people are asymptomatic or their symptoms can be similar to other nutritional deficiencies, a B12 deficiency may be hard to detect

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He is referenced here solely to recognize and honor his scientific contributions

DHODH comprises two distinct domains: An / barrel domain that extends into the mitochondrial matrix and a larger domain anchored to the membrane, which houses the binding sites for the substrate dihydroorotate and the coenzyme flavin mononucleotide (163166)