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A small, randomized, controlled, crossover trial involved 18 participants, average age 51 years, with obesity and prediabetes who underwent a 10-week intervention with cinnamon (4 grams per day) or placebo

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It is also important to ensure adequate folate levels through supplementation, if appropriate, once vitamin B12 supplementation has been commenced to avoid precipitating subacute combined degeneration of the spinal cord[2]