10.1016/j.ijbiomac.2024.136099 95 JiL.-L.ShengY.-C.ZhengZ.-Y.ShiL.WangZ.-T
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However, once therapy stops, appetite regulation typically normalizes within weeks
Materials and methods Mice NOD and NOD scid mice used at the University of Cambridge and B6(Cg)-Tyr c-2J /J (JAX #000058) or white C57BL/6, NOD.Rag2 -/- , NOD used at the Karolinska Institutet, Stockholm, Sweden, and white C57BL/6.Rag2 -/- mice used at the University of Lund (Sweden) were bred and maintained in a specific pathogen-free environment at the animal facilities and all procedures were approved by the ethical committee of Cambridge University, Karolinska Institutet, and Lund University Animal Care and Use, respectively