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Novos drugs were selected early this year for round two of price negotiations created by the Inflation Reduction Act, with yet-to-be-announced discounted prices set to take effect in 2027

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Risk factors include age over 65 years, history of peptic ulcer disease, concurrent use of anticoagulants or corticosteroids, and prolonged NSAID therapy

[3] Whilst the official documentation does not establish a link, some patients have reported musculoskeletal symptoms during treatment through spontaneous reporting systems such as the MHRA Yellow Card scheme