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First, sales of super-value brands have been increasing exponentially in Australia since the major increase in excise/customs duty in Australia in April 2010, well before the introduction of PP.9 ,5660 Second, the increase in the number of brandvariantpack size combinations available in the value segment predated the introduction of PP and indeed appeared to rely on packaging to emphasise product characteristics.35 Third, although excise/customs duty in Australia applies equally to every cigarette regardless of price segment, average recommended retail prices increased more for premium than for value brands after the August 2012 and February and August 2013 indexations of duty were accommodated.36 Fourth, the percentages of smokers who reported that they had tried a different brand because it was cheaper or thought about how much they were spending on cigarettes in the PP year 1 phase were no higher than in the pre-PP phase but were significantly higher after the December 2013 tax increase a year after introduction of PP

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The secretion of pro-inflammatory cytokines from cells treated with cellulose acetate indicated that this group of microplastics was recognized by PBMCs as an external adverse factor

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