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Additionally, schistosomal antigen provoked an immunomodulatory potential, as evidenced by a significant increase in serum interlukin-10 (IL-10), the percentage of splenic clusters of differentiation 4 T cells (CD4 + T cells), intestinal FoxP3 + Treg cells, and a significant decrease in serum IL-17 [55]

14 The extent of inflammatory infiltrate observed in hematoxylin and eosin-stained sections was similar among all treatment groups and the control group