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Description

Lysed cells (20 l) were transferred to a new 96-well plate and supplemented with 80 l water

WR conceived and designed the study, interpreted the data, and wrote the manuscript

Excessive decrease of ROS results in cellular damage, a phenomenon known as reductive stress (RedS) (53)

GCL catalyzes the first stage of the biosynthetic pathway where glutamate and cysteine are linked, creating -glutamyl-cysteine in the presence of ATP and Mg 2+ or Mn 2+