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Instead, these experts focused primarily on a small group of skeptics of the dangers of cigarettes during the 1950s, many of whom had or would eventually have ties to the tobacco industry

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A further limitation of the existing literature is that most population-based studies have classified cigarette smoking and e-cigarette use crudely, often treating e-cigarette use as a binary variable without distinguishing between exclusive e-cigarette users, dual users, and former smokers who no longer use any nicotine product

Nicotine e-cigarettes also increased abstinence (defined by the most rigorous criterion) compared to non-nicotine e-cigarettes (RR: 1.56