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Finally, this review primarily addresses established hallmarks of aging and does not encompass emerging or less-characterized pathways, leaving certain mechanisms open for future exploration

This is followed by PAD4-mediated histone citrullination, chromatin decondensation, and the formation of chromatin fibers [189]

For example, treatment with exendin-4 for 12 weeks in salt-sensitive obese db/db mice prevented the development of hypertension, despite increased intra-renal angiotensin II levels (Hirata et al

Wu C-P, Hsiao S-H, Huang Y-H et al (2020) Sitravatinib sensitizes ABCB1- and ABCG2-overexpressing multidrug-resistant cancer cells to chemotherapeutic drugs