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The severity of OA is closely associated with the levels of pyroptosis marker NLRP3 and inflammatory cytokines IL-1 and IL-18

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Anti-inflammatory effects are well-documented: GHK-Cu downregulates TNF- and other pro-inflammatory cytokines in wound models, shifting tissue from inflammatory to remodelling phase

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Future Perspectives of GLP-1 RA Use in People with T2D People with T2D are at higher risk of CV events compared with those without T2D, and CV disease is the major cause of death in people with T2D [97]

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