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doi: 10.1161/STROKEAHA.121.038151 129 MalhotraKKatsanosAHLambadiariVGoyalNPalaiodimouLKosmidouMet al

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However, isotope tracer studies confirm that TMA and TMAO are sequentially made from orally ingested l-carnitine in both mice and humans, and l-carnitine supplementation has been shown to accelerate atherosclerosis development in murine models of the disease (6, 26)