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In addition, both the GLP-1 insulinotropic effects and irisin levels are defective in T2D, and their exogenous administration is able to improve glycemic control [21, 22]

Individuals seeking medically guided weight loss Adults struggling with appetite control or cravings Those with a BMI in the overweight or obese range Individuals with insulin resistance or prediabetes (pending physician approval) Patients who have plateaued with diet and exercise alone People committed to combining medication with lifestyle changes Anyone wanting a structured, physician-led program with ongoing support Who Should Avoid GLP

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Cancer 144 , 136149 (2019)