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Seek immediate medical attention for sudden severe pain or signs of pancreatitis

Macrocytic anemia occurs when your body doesnt have enough normal red blood cells, and can cause symptoms including muscle weakness and paresthesias (paresthesias is the technical term for the pins and needles feeling on your skin)

Broyer M, Tete MJ, Guest G, Bertheleme JP, Labrousse F, Poisson M (1996) Clinical polymorphism of cystinosis encephalopathy

The orforglipron story reminds us that behind every breakthrough medication lies not just laboratory experimentation but sophisticated computational approaches that predict, optimize, and validate therapeutic potential