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Its structure enables stability in gastric acid, unlike many other peptides that degrade in acidic environments

Contraindications Do Not Use If You Have a personal or family history of medullary thyroid carcinoma (MTC) Have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Have had a serious hypersensitivity reaction to tirzepatide or any component of the formulation Are pregnant, planning to become pregnant, or breastfeeding Warnings and Precautions Acute pancreatitis: Has been reported in clinical trials

The side effect management strategies are identical for both medications, and most patients can manage effects with proper titration and lifestyle adjustments