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A recent head-to-head trial of the peptide drugs found that Lillys tirzepatide, which targets both GLP-1 and GIP receptors, produced greater average weight reductions than Novos semaglutide which targets only GLP-1

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The National Kidney Foundation recommends treatment of dialysis-related carnitine disorder symptoms with intravenous L-carnitine at 20 mg/kg of total body weight after each dialysis procedure

Keywords Bretylium Trade Name: generic Drug Class: Antiarrhythmic Mechanism of Action: (after an initial phase of causing the release of catecholamines) Interferes with the neuronal release of catecholamines Bretylium also lengthens the duration and effective refractory period in heart tissue (a Class III effect), an effect that is most pronounced in ischemic cells (which have shortened action potential durations) Indications: No longer available in the United States Previously used for attempted resuscitation from ventricular fibrillation after lidocaine and cardioversion have failed Side Effects: Precipitation of cardiac arrhythmias at the onset of drug therapy due to its ability to cause the initial release of catecholamines (when used as an antiarrhythmic)